
Dr M S Hiremath, affiliated to Ruby Hall Clinic, has conducted research in connection to smoking and amputation. He said, “A few people know and believe smoking can result in them losing their legs. It is the same atherosclerotic [cholesterol deposition] process that blocks the heart’s arteries and lead to heart disease. In Pune, out of the 100 cases that I see on an average every month, 20 are diagnosed with PVD; so one can imagine how serious this issue is becoming.”

“Smokers are likely to worsen their symptoms of PVD, and as a result increase their risk of amputation. Compared to smokers, people who quit smoking have less severe pain when walking and are less likely to develop pain at rest. They live longer, respond better to treatment, and are less likely to require amputation. Quitting smoking reduces the risk of PVD and the longer one has quit, the lower it becomes,” Hiremath added.
How PVD ruins your limbs
PVD occurs when the arteries (blood vessels) supplying blood to various parts of the body become narrow because of the build up of fatty deposits, which are sometimes called plaques or lesions, on the inside walls (linings) of the blood vessels. When the arteries that carry blood to your legs become too narrow because of deposit buildup, blood flow is reduced and the leg muscles do not get enough oxygen to support physical activity. This causes pain and is called ischaemia, which eventually leads to gangrene, and amputation.
Smoking is the number one risk factor for PVD and over 32% of people with PVD affecting the lower limbs are either smokers or ex-smokers
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Source: Times of India